ING4 (inhibitor of growth family, member 4)

Review on ING4 (inhibitor of growth family, member 4), with data on DNA, on the protein encoded, and where the gene is implicated

Hadronization via Coalescence

We review the quark coalescence model for hadronization in relativistic heavy ion collisions and show how it can explain the observed large baryon to meson ratio at intermediate transverse momentum and scaling of the elliptic flows of identified hadrons. We also show its predictions on higher-order anisotropic flows and discuss how quark coalescence applied to open- and hidden-charm mesons can give insight to charm quark interactions in the quark-gluon plasma and $J/\Psi$ production in heavy ion collisions.Comment: 6 pages, 4 figures, Proceedings of 20th Winter Workshop on Nuclear Dynamics, Trelawny Beach, Jamaica, March 15--20, 200

Performance Bounds for Parameter Estimation under Misspecified Models: Fundamental findings and applications

Inferring information from a set of acquired data is the main objective of any signal processing (SP) method. In particular, the common problem of estimating the value of a vector of parameters from a set of noisy measurements is at the core of a plethora of scientific and technological advances in the last decades; for example, wireless communications, radar and sonar, biomedicine, image processing, and seismology, just to name a few. Developing an estimation algorithm often begins by assuming a statistical model for the measured data, i.e. a probability density function (pdf) which if correct, fully characterizes the behaviour of the collected data/measurements. Experience with real data, however, often exposes the limitations of any assumed data model since modelling errors at some level are always present. Consequently, the true data model and the model assumed to derive the estimation algorithm could differ. When this happens, the model is said to be mismatched or misspecified. Therefore, understanding the possible performance loss or regret that an estimation algorithm could experience under model misspecification is of crucial importance for any SP practitioner. Further, understanding the limits on the performance of any estimator subject to model misspecification is of practical interest. Motivated by the widespread and practical need to assess the performance of a mismatched estimator, the goal of this paper is to help to bring attention to the main theoretical findings on estimation theory, and in particular on lower bounds under model misspecification, that have been published in the statistical and econometrical literature in the last fifty years. Secondly, some applications are discussed to illustrate the broad range of areas and problems to which this framework extends, and consequently the numerous opportunities available for SP researchers.Comment: To appear in the IEEE Signal Processing Magazin

Hadron production from quark coalescence and jet fragmentation in intermediate energy collisions at RHIC

Transverse momentum spectra of pions, protons and antiprotons in Au+Au collisions at intermediate RHIC energy of $\sqrt{s_{NN}}=62$ GeV are studied in a model that includes both quark coalescence from the dense partonic matter and fragmentation of the quenched perturbative minijet partons. The resulting baryon to meson ratio at intermediate transverse momenta is predicted to be larger than that seen in experiments at higher center of mass energies.Comment: 6 pages, 2 figures. Figures replaced to differentially address the high-pT behavior of baryon versus antibaryon to meson ratio

Effect of resonance decays on hadron elliptic flows

The influence of resonance decays on the elliptic flows of stable hadrons is studied in the quark coalescence model. Although difference between the elliptic flow of pions from resonance decays, except the rho meson, and that of directly produced pions is appreciable, those for other stable hadrons are small. Since there are more pions from the decays of rho mesons than from other resonances, including resonance decays can only account partially the deviation of final pion elliptic flow from the observed scaling of hadron elliptic flows, i.e., the hadron elliptic flow per quark is the same at same transverse momentum per quark. The remaining deviation can be explained by including the effect due to the quark momentum distribution inside hadrons.Comment: 13 pages and 5 figures, version pubblished in PRC, updated references and figure

Testicular histopathology, semen analysis and FSH, predictive value of sperm retrieval: supportive counseling in case of reoperation after testicular sperm extraction (TESE)

Background: To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE. The aim of our study was to determine the impact of different parameters, including testicular histopathology, on sperm retrieval in case of reoperation in patients undergoing testicular sperm extraction. Methods: We retrospectively analyzed 486 patients who underwent sperm extraction for intracytoplasmic sperm injection and testicular biopsy. Histology was classified into: normal spermatogenesis; hypospermatogenesis (reduction in the number of normal spermatogenetic cells); maturation arrest (absence of the later stages of spermatogenesis); and Sertoli cell only (absence of germ cells). Semen analysis and serum FSH, LH and testosterone were measured. Results: Four hundred thirty patients had non obstructive azoospermia, 53 severe oligozoospermia and 3 necrozoospermia. There were 307 (63%) successful sperm retrieval. Higher testicular volume, lower levels of FSH, and better histological features were predictive for sperm retrieval. The same parameters and younger age were predictive factors for shorter time for sperm recovery. After multivariable analysis, younger age, better semen parameters, better histological features and lower values of FSH remained predictive for shorter time for sperm retrieval while better semen and histology remained predictive factors for successful sperm retrieval. The predictive capacity of a score obtained by summing the points assigned for selected predictors (1 point for Sertoli cell only, 0.33 points for azoospermia, 0.004 points for each FSH mIU/ml) gave an area under the ROC curve of 0.843. Conclusions: This model can help the practitioner with counseling infertile men by reliably predicting the chance of obtaining spermatozoa with testicular sperm extraction when a repeat attempt is planne

Multiliteracies: Bringing Multimodality into Schools

Today’s technological advancements provide cause for literacy educators to think about literacy as many literacies or multiliteracies (Cimbricz & Rath, 2015). This analytical review explores the construct of multiliteracy in hopes of discovering how to help students become multiliterate and learn the many literacies important to today’s world. This review examines four case studies that speak to the actual impact multiliteracies has on student and teacher learning. My analysis suggests that in some cases, student engagement improved when the teaching and learning of multiliteracies were used in schools. Furthermore, the integration of multiple modes of meaning making seemed to better meet the needs of all students in the classroom. Unfortunately, mot much is known about multiliteracies, and its actual impact on student and teacher learning remains relatively unknown